Scores of published human studies, including double-blind clinical trials, establish that Flavay Plus® increases blood flow, improves nitric oxide levels and neurotransmitter activities, improves glucose metabolism in brain cells (all of which is essential to learning, memory and other cognitive functions) and thereby:
Studies show Flavay Plus® improves glucose metabolism in brain cells—which is essential to learning, memory and other cognitive functions. (127)
(Above:) PET imaging of the brain of a 59-year-old woman. The color scale indicates regional glucose metabolism at three brain levels, red is most intense and blue is least. UPPER: before Flavay Plus®; LOWER: after taking Flavay Plus® daily for three weeks. Metabolism is increased in almost all brain regions. (109, 125)
Decreased blood flow to the brain plays a major role in dementia and other brain disorders. The result is that the brain becomes starved for oxygen and fuel, producing a low-grade "suffocation." (455) Neurons become more active when blood flow increases. (14,231,339,455)
Licensed and sold for vascular health in France since 1950, the vascular protective activity of Flavay® has been established by many significant studies.
Clinical trials show Flavay® improves strength and tone of veins, arteries, capillaries (the smallest vessels) and lymphoid tissues by strengthening the essential constituents in vascular walls (collagen and elastin). (47,48,82,205)
Flavay® is shown to increase capillary resistance, decrease capillary permeability, and increase rate of lymph flow. (47,48,82,205)
By improving nitric oxide levels in brain cells, Flavay® supports regulation of the enzymes which control dopamine and norepinephrine, chemicals that carry messages among brain cells and are essential to memory, attention and problem-solving. (14,103,53,202-204,265,274)
Research shows taking Flavay® for six (6) weeks results in neuroprotective effects against cognitive decline. In vivo assays identified 13 proteins in the brain that are favorably mediated by Flavay®, "quantitatively in the opposite direction from previous findings for the same proteins in either Alzheimer's disease or ...neurodegeneration." (385)
(Above:) Flavay® protects cognitive function in multiple ways. In aging and neurodegenerative dysfunctions, neuronal death is triggered by neurotoxicity and/or neuroinflammation. Initiating factors include oxidative stress, DNA damage, protein aggregation and apoptotic (cell-death) cascades. Flavay® has demonstrated to protect the brain against cellular alteration through modulation of neuronal function against neurotoxicity and inhibition of glial-induced inflammation by: CysDA, 5-S-cysteinyldopamine; DHBT1, dihydrobenzothiazine 1; TNF-α, tumor necrosis factor-alpha; IL-1ß, interleukine-1 beta; CRP, C-reactive protein; NO, nitric oxide. Click here for scientific studies and references
Contains no GMOs, soy, sugar, salt, corn, milk, wheat, gluten, preservatives, artificial flavors or colors.
No pesticides, herbicides, heavy metals or GMOs. Flavay® is extracted from heritage Vitis vinifera grapes and the bark of Pinus maritima (French Maritime pine) trees grown exclusively in southwest France without using pesticides or herbicides or GMOs. Manufactured under strict ISO-9002 pharmaceutical regulations governed by the French Ministry of Health, Flavay® is rigorously tested, including for over 200 different pesticides.
Directions: As a dietary supplement, two capsules twice a day or as directed by your health professional.
Utilizing the dynamic interplay among the antioxidants and their cofactor nutrients, Flavay Plus® is a synergistic blend of clinically-proven, patented phytonutrients (in clinically-proven dosage amounts) with antioxidant vitamins and minerals formulated to boost both brain and immune functions.
FLAVAY®: Since 1950, Flavay® has been approved and sold in France for improved circulation. Human clinical studies show taking Flavay® strengthens collagen in vessel walls and improves circulation and microcirculation. Flavay® is a patented antioxidant and is shown to improve nitric oxide levels and improve cognitive response.
PHOSPHATIDYLSERINE: The original, clinically-proven and patented phosphatidylserine—derived from soy and purified so it's certified soy-free!
Essential to our diet, phosphatidylserine is found in every cell in our body, but most is in our brain. However, phosphatidylserine is deficient in modern diets, plus stress and aging cause deficiency. In Flavay Plus®, phosphatidylserine is a natural complex of phospholipids and fatty-acids proven to activate cell membranes, and to restore acetylcholine and dopamine—essential to memory, attention and problem-solving. The subject of many human clinical trials regarding memory loss, mood, cognitive performance, learning ability, stress, and prevention of, and significant improvement in, exercise-induced stress hormone levels. Thousands of published studies, many published in peer-reviewed mainstream scientific journals, including at least 64 human clinical trials, show daily doses of phosphatidylserine in Flavay Plus® can rejuvenate your brain cell membranes and benefit virtually every brain function. (106-112)
GABA: One of the most abundant neurotransmitters in our brain, persons with anxiety, panic disorders and depression may not produce sufficient levels of GABA. (148-150)
VITAMIN A (as Beta-carotene): The preferred form of vitamin A, beta-carotene is converted into vitamin A only as your body needs it. What remains is a powerful antioxidant shown to strengthen your immune system, reduce the risk of atherosclerosis, heart attack and stroke, and protect against macular degeneration and formation of cataracts. Flavay Plus® provides the highest quality full-spectrum array of plant-derived, antioxidant carotenoids: beta-carotene, alphacarotene, cryptoxanthin, zeaxanthin, lutein, and lycopene. (9,11-13,165,170)
VITAMIN B-1 (Thiamin): Plays an essential role in metabolism of carbohydrates in our body, improves mental attitude, and keeps our nervous system and muscles and heart functioning normally. Inadequate intake may result in mental illness and some psychiatrists, typically with medication, use vitamin B-1 for various emotional and psychiatric illnesses. (9,11-13,157)
VITAMIN B-2 (Riboflavin): Assists in energy metabolism, fatty and amino acid synthesis. Vitamin B-2 is needed for tissue repair and is sometimes called the "growth vitamin." Inadequate intake of vitamin B-2 may cause depression, moodiness, nervousness and irritability. (9,11-13,152,158)
VITAMIN B-6 (Pyridoxine): Involved in the metabolism of amino acids (the building blocks of proteins) and of essential fatty acids, our nervous system is dependent on vitamin B-6 for production of GABA and neurotransmitters in our brain such as serotonin and dopamine. It may be difficult for men and women to obtain even the RDAs from food. In addition, stress, medications, smoking and pollutants raise the B-6 requirement. Inadequate intake is associated with depression, confusion, dizziness, insomnia, irritability and nervousness. (9,11-13,151-158)
FOLATE: is vital for healthy cell division and replication and tissue growth. Folate is a natural form of vitamin B-9 which, along with vitamin B-12, is essential in the metabolism of amino acids, the synthesis of proteins, and in production of RNA and DNA. Folate, along with B-12, is needed for proper formation and regeneration of red blood cells and to break down homocysteine, lowering the risk of heart disease. Folate is also important for normal neurotransmitter function. Some studies suggest a folate deficiency can produce major mental problems and mood changes, including depression, schizophrenia and dementia. Low levels may also be connected with forms of mental retardation and low IQ. Folate is often deficient in the American diet and many medications can cause a deficiency. (9,11-13)
VITAMIN B-12 (Methylcobalamin): Helps our body to utilize fats, carbohydrates and protein; and to maintain a healthy nervous system. Vitamin B-12 increases energy, relieves irritability and improves concentration, memory and balance. Vitamin B-12 also helps our body to form and regenerate red blood cells and to break down homocysteine, lowering the risk of heart disease. In children, vitamin B-12 supports growth. (9,11-13)
VITAMIN C: Water-soluble, a free-radical scavenger, recycles vitamin E, plays a primary role in formation of collagen, prevents oxidation of LDL cholesterol and is essential for a strong immune system. Controlled studies prove the contribution of vitamin C to prevention and treatment of infectious, degenerative and stress diseases, to resistance against pollution and its supportive role in the manufacture of white blood cells and interferon. The half-life of vitamin C is only about 30 minutes in blood plasma, so Flavay Plus® with BioMor® C is preferred because once-a-day use provides your body with vitamin C protection all-day, as it naturally recycles vitamin C in your body by utilizing the synergistic interplay between the antioxidant vitamin and its cofactor antioxidant, Flavay®. (9,11-13)
VITAMIN E: Our body's principal fat-soluble antioxidant. Much of our body's free radical damage occurs in fats, such as cholesterol, and in fatty membranes of cells—exactly where vitamin E protects our body. Vitamin E is used by surgeons before and after operations to ensure against thrombosis and to increase immunity to infection, by pediatricians to prevent blindness in premature babies, and by other specialists to increase high-density lipoproteins. Vitamin E decreases elevated hormone levels and prevents and treats anemias. Flavay Plus® uses cold-water dispersible (dry powder) vitamin E because it is efficiently absorbed even when taken on an empty stomach or with a low-fat meal. Cold-water dispersible vitamin E is twice as expensive as non-cold water dispersible (oil) forms of vitamin E, but the cold-water form in Flavay Plus® is more efficiently absorbed. Also, Flavay Plus® uses only natural (D-alpha) vitamin E because it's safer and substantially more effective (according to The National Academy of Science) than synthetic (DL-alpha) vitamin E which is made from petrochemicals. (9,11-13,160-164)
SELENIUM: Necessary for our body's production of its own naturally-occurring antioxidants, including thioredoxin reductase and glutathione, a key intracellular antioxidant enzyme system responsible for protecting all our body's cells from free radical damage and detoxifying noxious agents from the body. Selenium also has a synergistic effect with vitamin E, which means the two combined are more powerful than either alone. Many Americans do not consume even the small RDA of selenium in their diet−which is dangerous to our health. Low blood levels of selenium have been strongly associated with an increased risk of heart attack, stroke and other types of diseases. (9,11-13)
ZINC: as zinc orotate, the most readily-absorbable form of zinc. Research shows zinc orotate is more neutrally charged than other forms of zinc, improving bioavailability and antioxidant properties.
Zinc is an essential mineral and has many important effects on our brain and immune system including neurotransmitter production and enzyme functioning. Stress, physical and mental, cause our body's zinc levels to fall. Zinc is a necessary part of our body's production of DHA and a constituent of many vital enzymes including superoxide dismutase which is a critical cellular antioxidant enzyme responsible for mopping up peroxynitrite (the highly toxic free-radical produced in abundance in normal immune system battles, as in viral or bacterial infections) and plays a powerful role in inflammation. Together with B vitamins, zinc assists in the utilization of insulin and glucose. There is a growing body of evidence to indicate that zinc is needed for the proper maintenance of vitamin E levels in our blood and aids in the absorption of vitamin A. Other important functions of zinc include promotion of glandular and reproductive health. There is strong evidence that zinc is required for the synthesis of the nucleic acids RNA and DNA which are essential for cell repair and cell growth. Studies found large percentages of apparently healthy children are deficient in zinc. (9,11-13,159)
Flavay Plus® is a brain-strengthening formula made of the highest-quality, proven ingredients in clinical doses, providing the best nutritional science has to offer.
My husband swears by Flavay Plus. He's a truck driver and Flavay Plus keeps him calm and at the same time his energy lasts long. He wouldn't do without it. —Ms. C.K.*
My psychologist husband told me that the difference in my behavior and focus is huge since taking Flavay and Flavay Plus. I am definitely ADD but was never diagnosed as a child. He is amazed at the changes in me, as am I. —Ms. Danielle S.*
Taking Flavay Plus and I feel strong. —Mr. W.P.*
My husband swears by Flavay Plus. He's a truck driver and Flavay Plus keeps him calm and at the same time his energy lasts long. He wouldn't do without it. —Ms. C.K.*
Flavay plus is still the only product that works to combat my ADHD without prescription medication. I am so thankful! —Ms. D.G.*
After a few weeks of taking Flavay Plus, I felt like someone turned on a light bulb, I was just stunned. Now my husband is taking it too. —Ms. Susan F.*
I started taking Flavay and Flavay Plus for depression in January of this year. I’m very satisfied to have no withdrawal periods and no depression. I know it works because I stopped taking the products and my husband said he could tell the difference, that I wasn't 'as nice a person' when I didn't take them. And I could tell, too. So I started taking them again. —Ms. E.R.*
My psychologist husband told me that the difference in my behavior and focus is huge since taking Flavay and Flavay Plus. I am definitely ADD but was never diagnosed as a child. He is amazed at the changes in me, as am I. —Ms. Danielle S.*
My ADD is so bad I cannot go a day without Flavay Plus. It actually helps me to stay awake in the afternoon at work and not need coffee. —Ms. D.G.*
I gave my son 2 capsules of Flavay Plus this morning before school and I took 2 capsules myself. A few hours into the school day, my son's teacher sent me an email saying that my son is like a new child, focused and alert. She wanted to know what happened... My husband is a medical doctor. He had cautioned me not to get excited when ordering it... and you know what, I feel more focused myself, more able to handle things. —Ms. C.L.*
I stopped taking Zoloft in 2006 because it made me sick. That's when I found Flavay and Flavay Plus and I've been taking it ever since (12 years) and it gets me going every day. Such a difference in my life. It's been very good for me. My wife takes it too. —Mr. P.Z.*
I know taking vitamins is good for you but this is much more than that. Because of taking Flavay and Flavay Plus I experience substantial improvement in mental sharpness, acuity and in the ability to react quickly and stay on top of situations while auto racing. —dentist*
I just wanted to write and say WOW... I was so skeptical of your product at first and really had a negative attitude when I started taking it. I am a 40 yr old female with anxiety, mild ADHD and a host of arthritis and inflammation issues. It was a struggle for me to get out of bed everyday and focus on what needed to be done. I had no focus, no attention span, no energy, and no desire to do anything. About a week into taking Flavay and Flavay Plus, I started noticing that I could think a little clearer. My rheumatoid arthritis flare-ups weren't so bad, though I still have them. feeling better, and having more energy. I never thought I would feel like my old self again. I don't know exactly how you do it,...but this stuff works! I am telling all of my friends to try it because you've given me my old life back! Thank you! —Ms. L.A.*
I have used Flavay and Flavay Plus for almost a month and I really have not felt this healthy for so long. Fantastic energy and better overall. I have ms (small letters intentional, I hate it) and am feeling better even at work, people have commented my skin is better than it has ever been. I have great energy, it is incredible. —Mr. G.S.*
After one month of taking Flavay and Flavay Plus, I feel really good. I feel younger, like I used to feel 5 years ago, so that I want to start a business, and other things like that. My wife says I even look different. —Mr. R.K.*
I take 4 capsules of Flavay Plus every morning and I can keep going all day, and I stay focused too. —Mr. T.C.*
I want to thank you for Flavay Plus, it's just wonderful. My anxiety, panic and stress levels plummeted and my skin became clear and radiant. —Ms. J.C.*
I began giving my daughter Flavay Plus for ADD and then I decided to add Flavay for my daughter's allergies. I want to tell you, the Flavay works like a charm for my daughter’s allergies. She is 6 years old, and when we ran out of capsules this week she told me, "You've got to get more Flavay!" —Ms. S.S.*
My son was born with a cleft palate and learning disabilities. I am no believer in nutrients but Flavay Plus is helping my son to calm down and stay on task. I recently ran out and my son told me that 'not taking Flavay Plus makes me act crazy,' so I know he can tell the difference. —Ms. E.W.*
I'm 26 and have a severe case of ADHD, and just recently started taking Flavay Plus. From the first week I was taking three to four pills per day, and feeling the results quite rapidly... I'm thrilled with the results I'm getting with Flavay Plus. —Ms. T.A.*
Flavay Plus has worked amazingly for my son in school. I don't have the same issue with ADHD like he does but I started taking it just because I saw what it did for him and it's helped so much with making me sharper and more clear minded. —Ms. A.M.*
I have had my son on Flavay Plus now for a couple months and his test scores have dramatically improved in school!!! —Ms. M.H.*
It's (Flavay) working! My grandson is doing so much better in school. No more bad text messages from his teacher. I am so grateful. I'm so happy. —Ms. M.P.*
After two weeks my mom (85, with dementia) is telling me she feels good because she is remembering better. I’m very upbeat over this. Flavay Plus is doing just what you thought it would for my mom. —Ms. X.M.*
I ordered Flavay Plus for my son because he just started a job. He said it helps his concentration and really missed your product. —Mr. F.C.*
My sister has been using Flavay Plus and she tried to get me to order it but I resisted. Now my sister is doing better about remembering and focusing while I'm still suffering, so I’ve got to get some for myself. —Ms. Mary C.*
Flavay is terrific. I've had concentration problems, well, for 60 years, all my life. I couldn't have direct eye contact with people when talking with them because I couldn't concentrate. I told jokes but couldn't make people laugh because I couldn't keep my concentration. Now I can look people in the eye. Now I can make people laugh! I don't know how it works but it works and it is terrific. —Mr. Wayne M.*
I've got to have my Flavay. Keeps me going. Keeps me young. 4 Flavay every day. —Mr. C.S.*
My 13-year-old son started taking Flavay for ADD. He came home from school saying, ‘Mom! I felt so smart! I answered all of the questions!’ The teacher backed him up, saying he got every answer correct. So I will keep giving him Flavay. —Ms. Tammy A.*
Flavay works well with my son (6 years-old, with Autism). He's doing work at the proper level, anger issues are gone. —Ms. O.F.*
Thank you so much for all your help. Thank you for also improving my son's lifestyle (taking Flavay). —Ms. R.D.*
My grandson asked to start taking Flavay again. He is 14 years old and has ADD and anxiety and pain going down his arms and so Flavay must have been helping him because he is asking for it. (Follow-up:) Flavay is working! My grandson is doing so much better in school. No more bad text messages from his teacher. I am so grateful. I'm so happy. —Ms. M.P.*
I have found Flavay to be a wonderful product. I buy it for my mum's eyes, but we also notice it improves her cognitive function. —Ms. N.S.*
Your Flavay Plus is wonderful! I'm a nurse and I don't dare tell the doctors what my son is taking, you know they don't like supplements. This product is amazing. I put it in my son's food, he doesn't even know he is taking it. Thanks again for a wonderful product. —Ms. R. Lee*
I do a lot of crossword puzzles and Boom! I just have to tell you that taking Flavay Plus and I can really tell a difference! Boom! It's very noticeable! —Ms. S. F.*